Ponce Health Sciences University
Contact: rnoel@psm.edu
Professional Preparation
– Boston College, Chestnut Hill, MA – BS in Biology 1993
-University of Wisconsin, Madison, WI – PhD in Biochemistry 1998
-Ponce School of Medicine, Ponce, PR – post doctoral studies (Pharmacology) 1998-2001
Publications
V. Rivera-Amill, R.J. Noel Jr., S. Orsini, G. Tirado, J.M.Garcia, S.Buch, and A. Kumar (2007) Variable Region 4 of SIV Envelope Correlates with Rapid Disease Progression in Morphine-exposed Macaques Infected with SIV/SHIV. Virology. 358(2), pp. 373-383.
R.J. Noel Jr. and A. Kumar. (2007) SIV vpr evolution is inversely related to disease progression in a morphine-dependent rhesus macaque model of AIDS. Virology. 359(1), pp.397-404.
A. Perez-Casanova, R.J. Noel Jr., V. Rivera-Amill, K. Husain, and A. Kumar. (2007) Morphine mediated deterioration of oxidative stress leads to rapid disease progression in SIV/SHIV-infected macaques. AIDS Res. Hum. Retrovir. 23(8), pp.1004-7.
A.Perez-Casanova, K. Husain, R.J. Noel Jr., V. Rivera-Amill and A. Kumar. (2008) Interaction of SIV/SHIV Infection and Morphine on Plasma Oxidant/Antioxidant Balance in Macaque. Mol. Cell. Biochem.308(1-2), pp. 169-175.
R. Noel, V. Rivera-Amill, S. Buch, and A. Kumar. (2008). Opiates, immune system, AIDS and non-human primate model. J. Neurovirol. 14 (4), pp.279-285.
V. Rivera-Amill, R. Noel, S. Buch, and A. Kumar. (2009). Analysis of the
V1V2 region of SIV envelope in the brains of morphine-dependent and control SIV/SHIV-infected macaques. AIDS Res. Hum. Retrovir. 25 (5), pp.532-4.
Ongoing Research/Grants
NIH/NIGMS SC3GM106970 (Noel, PI) 08/01/13 – 07/31/17
Astrocytic HIV Nef causes learning impairment via inflammation and TGF signaling
This grant is focused on the role of transforming growth factor beta in driving the inflammation and learning impairment caused by Nef expression in the hippocampus of rats. NO OVERLAP.
NIH/NIMHD-G12 MD007579 RCMI (PI: Torres and Noel) 06/01/14 – 03/31/19
Title: RCMI Program at the Ponce School of Medicine
This award supports the administration and implementation of the pilot project program at the Ponce School of Medicine. Dr. Noel is a multi-PI (non-contact) and director of the research pilot project program.NO OVERLAP.
NIH/NIMHD-G12 MD007579 RCMI (PI: Torres and Noel) 06/01/14 – 03/31/19
Title: RCMI Program at the Ponce School of Medicine – Molecular and Genomics Core
This award is to support the operation of the PSM Molecular and Genomics Core Laboratory. Dr. Noel is the scientific director of this core. NO OVERLAP.
NIH/NIMHD-CTRC U54MD007587 (PI: Marcia Cruz Correa, MD) 07/01/14 – 04/30/19
Title: Puerto Rico Clinical and Translational Research Consortium
Sub-component leader: Noel, Richard
This award will be to support the Translational Resources for Core Laboratories component at the Ponce School of Medicine for which Dr. Noel is the leader. NO OVERLAP.